The Endocannabinoid System (ECS)

Updated: Aug 26, 2020

It is really hard to understand cannabis/marijuana and how it may help a person without first understanding how are bodies are designed to work and what happens when it doesn't. Hopefully, this basic education will help you to better understand your body.


Our bodies are made up of several systems. You can probably name at least a few of them yourself. Each system has a function and they are dependent on other. What most of us don’t know is that we also have what is called an ENDOCANNABINOID SYSTEM…no, its not taught in mainstream schools yet. But it is critical to so many aspects of our body.

The ENDOCANNABINOID SYSTEM or ECS is responsible for keeping our body’s systems in BALANCE with each other. When our body is in balance and all systems are in good shape, the ECS is quiet – shut off so to speak. BUT when something happens that throws out body out of balance – the ECS turns on. It works like a walkie talkie in that it sits and listens to the body and waits for a problem then activates by producing and releasing endocannabinoids (cannabinoids our body makes) called ANANDAMIDE and 2AG that are sent to the source of the problem. Once the problem is resolved, the ECS then produces and releases a couple of enzymes called FAAH and MAGL to inactivate the Anandamide and 2AG and the ECS system shuts back down and resumes “LISTENING” for the next problem.

Here is an example:


Have you ever been walking along, minding your own business in your house and you are “balanced” or “stable” with not a care in the world when suddenly you stub your toe on the bed or the corner of a chair or table? OF COURSE YOU HAVE! It hurts REALLY bad right? You might even scream or yell…you are now OUT OF BALANCE! Your toe is throbbing, probably red and you are in extreme pain that you cannot stop – right? I know you are cringing with me. 
 Here is what happens as soon as that toe came in contact with the table/chair/bed. That pain prompted your ECS to activate – it produces ANANDAMIDE to stop the pain and 2 AG to stop the redness and inflammation. Once everything is OK and you can breathe again, you see the toe is not broken, bruised or something more severe, the ECS produces and releases the FAAH and MAGL and then the ECS shuts back off. Crisis resolved and body back in balance. 

These endocannabinoids are much like the cannabinoids in cannabis/marijuana called phytocannabinoids.

Anandamide is like THC in many ways and 2 AG is much like CBD – the 2 most common elements in cannabis.

When our bodies are over stressed, compromised or damaged – our ECS isn’t able to work as it is designed – THAT is where medical marijuana/cannabis can help. It can provide the body what it is used to making itself and because it is a plant and bio-available, the body recognizes it immediately and doesn’t have to figure it out, break it down or prepare for additional side effects or damage. It simply uses it.


Cannabis is not a magic potion, snake oil or cure all – it is a plant, it is medicine, and it needs to be treated as such...


If you need cannabis, you also need someone that can help you determine what and how to use it to be safe and successful.That’s where I, as an RN and Cannabis Nurse come in.Every patient deserves a nurse and I am here for you.You’ll be posting loads of engaging content, so be sure to keep your blog organized with Categories that also allow visitors to explore more of what interests them.

The information provided on the 2 Leaf Nurses website and blog is for educational purposes ONLY. If you have questions about what a cannabis nurse can do for you, please click here to contact 2 Leaf Nurses [SS1] or call 417-812-7676 today.

[SS1]http://www.2leafnurses.com/contact-us

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The information provided on the 2 Leaf Nurses website and blog is for educational purposes ONLY. Nothing contained within this website should be construed as nor is intended to be used for medical diagnosis or treatment. This information should not be used in place of the advice of your physician or other qualified health care provider. Always consult with your physician or other qualified health care provider before embarking on a new treatment, diet, or fitness program. You should never disregard medical advice or delay seeking it because of any information on this website. If you have questions about what a cannabis nurse can do for you, please click here to contact  2 Leaf Nurses or call 417-812-7676  today.

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